Kisspeptin-10, human (TFA)
CAS No. ——
Kisspeptin-10, human (TFA) ( —— )
产品货号. M30044 CAS No. ——
Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Kisspeptin-10, human (TFA)
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.
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产品描述Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.(In Vitro):Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells.(In Vivo):Intravenous infusion of kisspeptin-10 (7.5, 35, and 100 nM) induces a dose-dependent increase in LH secretion. The stimulatory effect of kisspeptin-10 (100 n nM) on LH secretion is blocked by the GnRH antagonist cetrorelix, precluding a singular action on gonadotropes. Kisspeptin-10 inhibits angiogenesis in vivo. Kp-10 inhibits tumor growth in SCID mice xenografted with human prostate cancer cells (PC-3) through inhibiting tumor angiogenesis.
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同义词——
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通路Others
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靶点Other Targets
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受体GPR54
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量1416.5
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分子式C63H83N17O14.C2HF3O2
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纯度>98% (HPLC)
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溶解度H2O : 4 mg/mL (2.82 mM; Need ultrasonic)
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SMILES——
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化学全称Sequence:Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Son HE, et al. Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation. Sci Rep. 2018 Feb 1;8(1):2134.
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