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Kisspeptin-10, human (TFA)

CAS No. ——

Kisspeptin-10, human (TFA) ( —— )

产品货号. M30044 CAS No. ——

Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    Kisspeptin-10, human (TFA)
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.
  • 产品描述
    Kisspeptin-10, human TFA, is an effective vasoconstrictor and angiogenesis inhibitor.Kisspeptin-10, human TFA inhibits tumor metastasis through its receptor GPR54.The kisspeptin-10-gpr54 system plays an important role in embryonic kidney development.(In Vitro):Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells.(In Vivo):Intravenous infusion of kisspeptin-10 (7.5, 35, and 100 nM) induces a dose-dependent increase in LH secretion. The stimulatory effect of kisspeptin-10 (100 n nM) on LH secretion is blocked by the GnRH antagonist cetrorelix, precluding a singular action on gonadotropes. Kisspeptin-10 inhibits angiogenesis in vivo. Kp-10 inhibits tumor growth in SCID mice xenografted with human prostate cancer cells (PC-3) through inhibiting tumor angiogenesis.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    GPR54
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    ——
  • 分子量
    1416.5
  • 分子式
    C63H83N17O14.C2HF3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O : 4 mg/mL (2.82 mM; Need ultrasonic)
  • SMILES
    ——
  • 化学全称
    Sequence:Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Son HE, et al. Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation. Sci Rep. 2018 Feb 1;8(1):2134.
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